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MONITORING OF PRODUCTION LEVEL OF RECOMBINANT HUMAN PROLONGED LACTATION LACTOFERRIN IN MILK OF GENETICALLY MODIFIED GOATS DURING

Abstract

The paper presents the results of monitoring of production level of recombinant human lactoferrin in milk of genetically modified goats during prolonged lactation. Concentration of recombinant human lactoferrin has been determined in milk of transgenic goats F3, F4, F5 during prolonged lactation. It has been found that concentration of recombinant human lactoferrin in animal’s milk had been in the range of 4.4-7.01 g/l for 10 months. The average value of this indicator was recorded at the level of 6.25±10 g/l, median - 6.36 g/l or 0.62% in 1 liter of milk. The results obtained indicate stable secretion of recombinant human lactoferrin by mammary gland cells of udder of transgenic animals F3, F4, F5.

About the Authors

E. V. Petrushko
Research and Practical Center of the National Academy of Sciences of Belarus for Animal Breeding
Russian Federation


D. M. Bogdanovich
Research and Practical Center of the National Academy of Sciences of Belarus for Animal Breeding
Russian Federation


А. I. Budevich
Research and Practical Center of the National Academy of Sciences of Belarus for Animal Breeding
Russian Federation


V. N. Kuznetsova
Research and Practical Center of the National Academy of Sciences of Belarus for Animal Breeding
Russian Federation


N. L. Zaremba
Research and Practical Center of the National Academy of Sciences of Belarus for Animal Breeding
Russian Federation


Т. N. Brovko
Research and Practical Center of the National Academy of Sciences of Belarus for Animal Breeding
Russian Federation


References

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Review

For citations:


Petrushko E.V., Bogdanovich D.M., Budevich А.I., Kuznetsova V.N., Zaremba N.L., Brovko Т.N. MONITORING OF PRODUCTION LEVEL OF RECOMBINANT HUMAN PROLONGED LACTATION LACTOFERRIN IN MILK OF GENETICALLY MODIFIED GOATS DURING. Zootechnical Science of Belarus. 2020;55(2):255-262. (In Russ.)

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ISSN 0134-9732 (Print)