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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zootech</journal-id><journal-title-group><journal-title xml:lang="ru">Зоотехническая наука Беларуси</journal-title><trans-title-group xml:lang="en"><trans-title>Zootechnical Science of Belarus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0134-9732</issn><publisher><publisher-name>Научно-практический центр Национальной академии наук Беларуси по животноводству</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">zootech-411</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГЕНЕТИКА, РАЗВЕДЕНИЕ, СЕЛЕКЦИЯ, БИОТЕХНОЛОГИЯ РАЗМНОЖЕНИЯ И ВОСПРОИЗВОДСТВО</subject></subj-group></article-categories><title-group><article-title>АНАЛИЗ РАЗЛИЧНЫХ ПОПУЛЯЦИЙ КРУПНОГО РОГАТОГО СКОТА НА НАЛИЧИЕ МУТАЦИИ BLAD В ГЕНЕ CD18</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of Different Cattle Populations on Presence of BLAD Mutation in CD18 Gene</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Епишко</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Epishko</surname><given-names>T. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курак</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurak</surname><given-names>O. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>РУП «Научно-практический центр Национальной академии наук Беларуси по животноводству»</institution></aff><aff xml:lang="en"><institution>RUE "Scientific and Practical Center of the National Academy of Sciences of Belarus on Animal Husbandry"</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>12</day><month>08</month><year>2022</year></pub-date><volume>42</volume><issue>0</issue><fpage>66</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Епишко Т.И., Курак О.П., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Епишко Т.И., Курак О.П.</copyright-holder><copyright-holder xml:lang="en">Epishko T.I., Kurak O.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://zootech.belal.by/jour/article/view/411">https://zootech.belal.by/jour/article/view/411</self-uri><abstract><p>Проведен анализ различных популяций крупного рогатого скота по локусу гена CD18, выявивший наличие точковой мутации BLAD в данном гене. Выявлено варьирование частоты встречаемости генотипов CD18ВL/ТL - носителей мутации в зависимости от популяции и половозрастной группы животных: у коров - 0-11,8 %, быков-производителей - 0-4,8 %, ремонтных бычков - 0,9 %.</p></abstract><trans-abstract xml:lang="en"><p>Analysis of different cattle populations on gene locus CD18 was carried out. It revealed presence of dot mutation of BLAD in this gene. Variance of genotype CD18BL/TL frequency was determined. CD18BL/TL - mutation carrier depending on population and sex-age group of animals: cows - 0-11,8%; bulls-producers - 0,4,8%; replacement calves - 0,9%.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>крупный рогатый скот</kwd><kwd>метод ПЦР - ПДРФ</kwd><kwd>мутация BLAD (синдром иммунодефицита)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cattle</kwd><kwd>PCR-RFLP</kwd><kwd>BLAD mutation (immunodeficiency syndrome)</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Molecular definition of the bovine granulocytopathy syndrome: identification of deficiency of the Mac-1 (CD11b/CD18) glycoprotein / V. E. Kehrli [at el.] // Am. J. Vet. Res. - 1990. - Vol. 51, № 11. - P. 1826-1936.</mixed-citation><mixed-citation xml:lang="en">Molecular definition of the bovine granulocytopathy syndrome: identification of deficiency of the Mac-1 (CD11b/CD18) glycoprotein / V. E. 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